Pint/(Pint+kaPint_PTS_Glc)*(kiFBP_PTS_Glc/(FBP+kiFBP_PTS_Glc))*Vmax_PTS_Glc*(Glucose/kmGlucose_PTS_Glc)*(PEP/kmPEP_PTS_Glc)/((1+Glucose/kmGlucose_PTS_Glc)*(1+PEP/kmPEP_PTS_Glc)+(1+G6P/kmG6P_PTS_Glc)*(1+PYR/kmPYR_PTS_Glc)-1)
Vmax_ATPase*((ATP/kmATP_ATPase)^nATPase/((ATP/kmATP_ATPase)^nATPase+1))
kiPint_Ptransport/(Pint+kiPint_Ptransport)*Vmax_Ptransport*(ATP/kmATP_Ptransport)*(Pext/kmPext_Ptransport)/((1+Pext/kmPext_Ptransport)*(1+ATP/kmATP_Ptransport)+(1+Pint/kmPint_Ptransport+(Pint/kmPint_Ptransport)^2)*(1+ADP/kmADP_Ptransport)-1)
(Vmax_PGI*(G6P/kmG6P_PGI)-Vmax_PGI/Keq_PGI*(F6P/kmG6P_PGI))/(1+G6P/kmG6P_PGI+F6P/kmF6P_PGI)
Vmax_PFK*(F6P/kmF6P_PFK)*(ATP/kmATP_PFK)/((1+F6P/kmF6P_PFK)*(1+ATP/kmATP_PFK)+(1+FBP/kmFBP_PFK)*(1+ADP/kmADP_PFK)-1)
(Vmax_FBA*(FBP/kmFBP_FBA)-Vmax_FBA/Keq_FBA*(G3P^2/kmFBP_FBA))/(1+FBP/kmFBP_FBA+G3P/kmG3P_FBA+(G3P/kmG3P_FBA)^2)
(Vmax_GAPDH*(G3P/kmG3P_GAPDH)*(NAD/kmNAD_GAPDH)*(Pint/kmPint_GAPDH)-Vmax_GAPDH/Keq_GAPDH*(BPG/kmG3P_GAPDH)*(NADH/kmNAD_GAPDH)*(1/kmPint_GAPDH))/((1+G3P/kmG3P_GAPDH)*(1+Pint/kmPint_GAPDH)*(1+NAD/kmNAD_GAPDH)+(1+BPG/kmBPG_GAPDH)*(1+NADH/kmNADH_GAPDH)-1)
(Vmax_ENO*(BPG/kmBPG_ENO)*(ADP/kmADP_ENO)-Vmax_ENO/Keq_ENO*(PEP/kmBPG_ENO)*(ATP/kmADP_ENO))/((1+BPG/kmBPG_ENO)*(1+ADP/kmADP_ENO)+(1+PEP/kmPEP_ENO)*(1+ATP/kmATP_ENO)-1)
FBP/(FBP+kaFBP_PYK)*(kiPint_PYK^nPYK/(Pint^nPYK+kiPint_PYK^nPYK))*Vmax_PYK*(ADP/kmADP_PYK)*(PEP/kmPEP_PYK)/((1+ADP/kmADP_PYK)*(1+PEP/kmPEP_PYK)+(1+ATP/kmATP_PYK)*(1+PYR/kmPYR_PYK)-1)
FBP/(FBP+kaFBP_LDH)*(kiPint_LDH/(Pint+kiPint_LDH))*Vmax_LDH*(PYR/kmPYR_LDH)*(NADH/kmNADH_LDH)/((1+PYR/kmPYR_LDH)*(1+NADH/kmNADH_LDH)+(1+Lactate/kmLactate_LDH)*(1+NAD/kmNAD_LDH)-1)
kiG3P_PDH/(G3P+kiG3P_PDH)*(Vmax_PDH*(PYR/kmPYR_PDH)*(CoA/KmCoA_PDH)-Vmax_PDH/Keq_PDH*(AcetCoA/kmPYR_PDH)*(Formate/KmCoA_PDH))/((1+PYR/kmPYR_PDH)*(1+CoA/KmCoA_PDH)+(1+AcetCoA/kmAcetCoA_PDH)*(1+Formate/kmFormate_PDH)-1)
kiATP_AE/(ATP+kiATP_AE)*Vmax_AE*(AcetCoA/kmAcetCoA_AE)*(NADH/kmNADH_AE)^2/((1+NADH/kmNADH_AE+(NADH/kmNADH_AE)^2)*(1+AcetCoA/kmAcetCoA_AE)+(1+Ethanol/kmEthanol_AE)*(1+CoA/kmCoA_AE)*(1+NAD/kmNAD_AE+(NAD/kmNAD_AE)^2)-1)
Vmax_AC*(AcetCoA/kmAcetCoA_AC)*(ADP/kmADP_AC)/((1+AcetCoA/kmAcetCoA_AC)*(1+ADP/kmADP_AC)+(1+Acetate/kmAcetate_AC)*(1+ATP/kmATP_AC)*(1+CoA/kmCoA_AC)-1)
(Vmax_PA*(PYR/kmPYR_PA)^2-Vmax_PA/Keq_PA*(Acetoin/kmPYR_PA))/(1+PYR/kmPYR_PA+(PYR/kmPYR_PA)^2+1+Acetoin/kmAcetoin_PA-1)
(Vmax_AB*(Acetoin/kmAcetoin_AB)*(NADH/kmNADH_AB)-Vmax_AB/Keq_AB*(Butanediol/kmAcetoin_AB)*(NAD/kmNADH_AB))/((1+Acetoin/kmAcetoin_AB)*(1+NADH/kmNADH_AB)+(1+Butanediol/kmButanediol_AB)*(1+NAD/kmNAD_AB)-1)
kiF6P_MPD/(F6P+kiF6P_MPD)*(Vmax_MPD*(F6P/kmF6P_MPD)*(NADH/kmNADH_MPD)-Vmax_MPD/Keq_MPD*(Mannitol1Phosphate/kmF6P_MPD)*(NAD/kmNADH_MPD))/((1+F6P/kmF6P_MPD)*(1+NADH/kmNADH_MPD)+(1+Mannitol1Phosphate/kmMannitol1Phoshate_MPD)*(1+NAD/kmNAD_MPD)-1)
Vmax_MP*(Mannitol1Phosphate/kmMannitol1Phosphate_MP)/(1+Mannitol1Phosphate/kmMannitol1Phosphate_MP+1+Mannitol/kmMannitol_MP-1)
Vmax_PTS_Man*(Mannitol_Ext/kmMannitolExt_PTS_Man)*(PEP/kmPEP_PTS_Man)/((1+Mannitol_Ext/kmMannitolExt_PTS_Man)*(1+PEP/kmPEP_PTS_Man)+(1+Mannitol1Phosphate/kmMannitol1Phosphate_PTS_Man)*(1+PYR/kmPYR_PTS_Man)-1)
Vmax_Acetoin_transp*(Acetoin/kmAcetoin_Acetoin_transp)/(1+Acetoin/kmAcetoin_Acetoin_transp+Acetoin_Ext/kmAcetoin_Ext_Acetoin_transp)
Vmax_Mannitol_transp*(Mannitol/kmMannitol_Mannitol_transp)/(1+Mannitol/kmMannitol_Mannitol_transp+Mannitol_Ext/kmMannitol_Ext_Mannitol_transp)
Vmax_FBPase*(FBP/kmFBP_FBPase)/(FBP/kmFBP_FBPase+(1+F6P/kmF6P_FBPase)*(1+Pint/kmPint_FBPase))
2012-06-14T23:28:10Z
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<p>
<b>Computational Model of <i>L. lactis</i> Metabolism</b> created by Rafael Costa. INESC-ID, Lisboa, Portugal.</p>
<p>Published in Rafael S. Costa, Andras Hartmann, Paula Gaspar, Ana R. Neves and Susana Vinga (2014),
An extended dynamic model of <i>Lactococcus lactis</i> metabolism for mannitol and 2,3-butanediol production. <i>Molecular BioSystems</i>
<a href="http://pubs.rsc.org/en/content/articlelanding/2014/mb/c3mb70265k#!divAbstract">10.1039/C3MB70265K </a>
</p>
</body>
2012-06-14T23:44:30Z
2012-06-14T23:44:17Z
0 0 1.3217999014871e+020 1.08291358096138e+021 0 5.769979386595314e+020 0 7.016628328690636e+019 0 0 0 0 0 4.330522161189001e+020 0 0 0 3.011070895000001e+022 2.408856716e+022 0 3.576177219534769e+019 0 57552905377637.09 2.8304066413e+019 0 1.383028698287318e+020 0 1 0.047 1
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