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General Information
| Manuscript title | Dynamic modeling of the central carbon metabolism of Escherichia coli. |
| PubMed ID | 17590932 |
| Journal | Biotechnology and Bioengineering |
| Year | 2002 |
| Authors | Christophe Chassagnole, Naruemol Noisommit-Rizzi, Joachim W. Schmid, Klaus Mauch, Matthias Reuss |
| Affiliations | Institute of Biochemical Engineering, University of Stuttgart |
| Keywords | dynamic model, Escherichia coli, parameter fitting, flux control coefficients |
| Full text article |
Chassagnole_2002.pdf
|
| Project name | not specified |
| Data used for | Model building and Model validation |
Model Information
| Model name | Chassagnole2002_Carbon_Metabolism | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Organism | Escherichia coli | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Model type | ordinary differential equations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Category | Metabolism | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of reactions | 48 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of species | 18 + 7 co-metabolites | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of regulators | 6 activations + 7 inhibitions | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of parameters | 125 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Number of compartments | 2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Dilution rate (h-1) | 0.1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Model file(s) and history |
LATEST BIOMD0000000051.xml
(2014-03-19 14:31:21 UTC
by Administrator KiMoSys
)
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Preview file BIOMD0000000051.xml<?xml version='1.0' encoding='UTF-8' standalone='no'?>
<!-- This model was downloaded from BioModels Database -->
<!-- Wed Mar 06 19:13:34 GMT 2013 -->
<!-- http://www.ebi.ac.uk/biomodels/ -->
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<notes>
<body xmlns='http://www.w3.org/1999/xhtml'>
<p align='left'>The model reproduces Figures 4,5 and 6 of the publication. The analytical functions for cometabolites Catp, Camp, Cnadph, and Cnadp slightly differ from the equations given in the paper. These changes were made in consultation with Dr. Christophe Chassagnole and are essential for reproducing the figures. The dependency of the rate of change of extracellular glucose concentration on the ratio of biomass concentration to specific weight of biomass (Cx*rPTS/Rhox) is taken into account by appropriately adjusting the stoichiometries of the species involved in the phosphotransferase system (rPTS). The rmax values for the various reactions are obtained from experiments and are not provided in the paper. However, these were personally communicated to the JWS repository. The model has been successfully tested on MathSBML.</p>
<p align='left'> <font face='Arial, Helvetica, sans-serif'> <b> <a href='http://www.sbml.org/'>SBML</a>
level 2 code generated for the JWS Online project by Jacky Snoep using <a href='http://pysces.sourceforge.net/'>PySCeS</a>
<br/>
Run this model online at <a href='http://jjj.biochem.sun.ac.za/'>http://jjj.biochem.sun.ac.za</a>
<br/>
To cite JWS Online please refer to: Olivier, B.G. and Snoep, J.L. (2004) <a href='http://bioinformatics.oupjournals.org/cgi/content/abstract/20/13/2143'>Web-based
modelling using JWS Online</a>
, Bioinformatics, 20:2143-2144 </b>
</font>
</p>
<br/>
<p>To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to <a href='http://creativecommons.org/publicdomain/zero/1.0/' title='Creative Commons CC0'>CC0 Public Domain Dedication</a>
for more information. </p>
<p>In summary, you are entitled to use this encoded model in absolutely any manner you deem suitable, verbatim, or with modification, alone or embedded it in a larger context, redistribute it, commercially or not, in a restricted way or not.</p>
<br/>
<p>To cite BioModels Database, please use: <a href='http://www.ncbi.nlm.nih.gov/pubmed/20587024' target='_blank'>Li C, Donizelli M, Rodriguez N, Dharuri H, Endler L, Chelliah V, Li L, He E, Henry A, Stefan MI, Snoep JL, Hucka M, Le Novère N, Laibe C (2010) BioModels Database: An enhanced, curated and annotated resource for published quantitative kinetic models. BMC Syst Biol., 4:92.</a>
</p>
</body>
</notes>
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<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.chebi/CHEBI:17794'/>
<rdf:li rdf:resource='http://identifiers.org/kegg.compound/C00197'/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
</species>
<species compartment='cytosol' id='cpg2' initialConcentration='0.399' metaid='_704883' name='2-Phosphoglycerate'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_704883'>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.chebi/CHEBI:17835'/>
<rdf:li rdf:resource='http://identifiers.org/kegg.compound/C00631'/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
</species>
<species compartment='cytosol' id='cribu5p' initialConcentration='0.111' metaid='_704903' name='Ribulose-5-phosphate'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_704903'>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.chebi/CHEBI:17363'/>
<rdf:li rdf:resource='http://identifiers.org/kegg.compound/C00199'/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
</species>
</listOfSpecies>
<listOfParameters>
<parameter constant='false' id='catp' metaid='metaid_0000073' units='mM' value='4.27'/>
<parameter constant='false' id='cadp' metaid='metaid_0000076' units='mM' value='0.595'/>
<parameter constant='false' id='camp' metaid='metaid_0000077' units='mM' value='0.955'/>
<parameter constant='false' id='cnadp' metaid='metaid_0000078' units='mM' value='0.195'/>
<parameter constant='false' id='cnadph' metaid='metaid_0000079' units='mM' value='0.062'/>
<parameter constant='false' id='cnad' metaid='metaid_0000080' units='mM' value='1.47'/>
<parameter constant='false' id='cnadh' metaid='metaid_0000081' units='mM' value='0.1'/>
</listOfParameters>
<listOfRules>
<assignmentRule metaid='metaid_0000074' variable='catp'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<minus/>
<cn> 4.27 </cn>
<apply>
<times/>
<cn> 4.163 </cn>
<apply>
<divide/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<apply>
<plus/>
<cn> 0.657 </cn>
<apply>
<times/>
<cn> 1.43 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
<apply>
<times/>
<cn> 0.0364 </cn>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn type='integer'> 2 </cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule metaid='metaid_0000082' variable='cadp'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<plus/>
<cn> 0.582 </cn>
<apply>
<times/>
<cn> 1.73 </cn>
<apply>
<power/>
<cn> 2.731 </cn>
<apply>
<times/>
<cn> -0.15 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<cn> 0.12 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
<apply>
<times/>
<cn> 0.000214 </cn>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn type='integer'> 3 </cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule metaid='metaid_0000083' variable='camp'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<plus/>
<cn> 0.123 </cn>
<apply>
<times/>
<cn> 7.25 </cn>
<apply>
<divide/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<apply>
<plus/>
<cn> 7.25 </cn>
<apply>
<times/>
<cn> 1.47 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
<apply>
<times/>
<cn> 0.17 </cn>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn type='integer'> 2 </cn>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<divide/>
<cn> 1.073 </cn>
<apply>
<plus/>
<cn> 1.29 </cn>
<apply>
<times/>
<cn> 8.05 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule metaid='metaid_0000084' variable='cnadph'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<plus/>
<cn> 0.062 </cn>
<apply>
<times/>
<cn> 0.332 </cn>
<apply>
<power/>
<cn> 2.718 </cn>
<apply>
<times/>
<cn> -0.464 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<cn> 0.0166 </cn>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn> 1.58 </cn>
</apply>
</apply>
<apply>
<times/>
<cn> 0.000166 </cn>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn> 4.73 </cn>
</apply>
</apply>
<apply>
<times/>
<cn> 0.1312 </cn>
<apply>
<power/>
<cn type='integer'> 10 </cn>
<cn type='integer'> -9 </cn>
</apply>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn> 7.89 </cn>
</apply>
</apply>
<apply>
<times/>
<cn> 0.1362 </cn>
<apply>
<power/>
<cn type='integer'> 10 </cn>
<cn type='integer'> -12 </cn>
</apply>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn type='integer'> 11 </cn>
</apply>
</apply>
<apply>
<times/>
<cn> 0.1233 </cn>
<apply>
<power/>
<cn type='integer'> 10 </cn>
<cn type='integer'> -15 </cn>
</apply>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn> 14.2 </cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule metaid='metaid_0000085' variable='cnadp'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<plus/>
<apply>
<minus/>
<cn> 0.159 </cn>
<apply>
<times/>
<cn> 0.00554 </cn>
<apply>
<divide/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<apply>
<plus/>
<apply>
<minus/>
<cn> 2.8 </cn>
<apply>
<times/>
<cn> 0.271 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
</apply>
<apply>
<times/>
<cn> 0.01 </cn>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn type='integer'> 2 </cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
<apply>
<divide/>
<cn> 0.182 </cn>
<apply>
<plus/>
<cn> 4.82 </cn>
<apply>
<times/>
<cn> 0.526 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule metaid='metaid_0000086' variable='cnadh'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<plus/>
<cn> 0.0934 </cn>
<apply>
<times/>
<cn> 0.00111 </cn>
<apply>
<power/>
<cn> 2.371 </cn>
<apply>
<times/>
<cn> -0.123 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<cn> 0.844 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
<apply>
<times/>
<cn> 0.104 </cn>
<apply>
<power/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn type='integer'> 3 </cn>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
<assignmentRule metaid='metaid_0000087' variable='cnad'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<minus/>
<apply>
<plus/>
<cn> 1.314 </cn>
<apply>
<times/>
<cn> 1.314 </cn>
<apply>
<power/>
<cn> 2.73 </cn>
<apply>
<minus/>
<apply>
<times/>
<cn> -0.0435 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
<cn> 0.342 </cn>
</apply>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
<cn> 7.871 </cn>
</apply>
<apply>
<divide/>
<apply>
<power/>
<cn> 2.73 </cn>
<apply>
<minus/>
<apply>
<times/>
<cn> -0.0218 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
<cn> 0.171 </cn>
</apply>
</apply>
<apply>
<plus/>
<cn> 8.481 </cn>
<csymbol definitionURL='http://www.sbml.org/sbml/symbols/time' encoding='text'> t </csymbol>
</apply>
</apply>
</apply>
</apply>
</math>
</assignmentRule>
</listOfRules>
<listOfReactions>
<reaction id='vPTS' metaid='_704943' name='Phosphotransferase system'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_704943'>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.pathway/eco02060'/>
</rdf:Bag>
</bqbiol:is>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_515208' species='cglcex'/>
<speciesReference metaid='_515220' species='cpep' stoichiometry='65'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_515232' species='cg6p' stoichiometry='65'/>
<speciesReference metaid='_515244' species='cpyr' stoichiometry='65'/>
</listOfProducts>
<kineticLaw metaid='_515256'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> extracellular </ci>
<ci> rmaxPTS </ci>
<ci> cglcex </ci>
<apply>
<divide/>
<ci> cpep </ci>
<ci> cpyr </ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> KPTSa1 </ci>
<apply>
<times/>
<ci> KPTSa2 </ci>
<apply>
<divide/>
<ci> cpep </ci>
<ci> cpyr </ci>
</apply>
</apply>
<apply>
<times/>
<ci> KPTSa3 </ci>
<ci> cglcex </ci>
</apply>
<apply>
<times/>
<ci> cglcex </ci>
<apply>
<divide/>
<ci> cpep </ci>
<ci> cpyr </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<apply>
<power/>
<ci> cg6p </ci>
<ci> nPTSg6p </ci>
</apply>
<ci> KPTSg6p </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxPTS' metaid='_515268' units='mM_per_second' value='7829.78'/>
<parameter id='KPTSa1' metaid='_515280' units='mM' value='3082.3'/>
<parameter id='KPTSa2' metaid='_515292' units='mM' value='0.01'/>
<parameter id='KPTSa3' metaid='_515304' units='dimensionless' value='245.3'/>
<parameter id='nPTSg6p' metaid='_515316' units='dimensionless' value='3.66'/>
<parameter id='KPTSg6p' metaid='_515328' units='mM' value='2.15'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPGI' metaid='_704963' name='Glucose-6-phosphate isomerase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_704963'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_1255'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00771'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/5.3.1.9'/>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0004347'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_515340' species='cg6p'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_515352' species='cf6p'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid='_515364' species='cpg'/>
</listOfModifiers>
<kineticLaw metaid='_515376'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxPGI </ci>
<apply>
<minus/>
<ci> cg6p </ci>
<apply>
<divide/>
<ci> cf6p </ci>
<ci> KPGIeq </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> KPGIg6p </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cf6p </ci>
<apply>
<times/>
<ci> KPGIf6p </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cpg </ci>
<ci> KPGIf6ppginh </ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<divide/>
<ci> cpg </ci>
<ci> KPGIg6ppginh </ci>
</apply>
</apply>
</apply>
<ci> cg6p </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxPGI' metaid='_515388' units='mM_per_second' value='650.9878687'/>
<parameter id='KPGIeq' metaid='_515401' units='dimensionless' value='0.1725'/>
<parameter id='KPGIg6p' metaid='_515413' units='mM' value='2.9'/>
<parameter id='KPGIf6p' metaid='_515425' units='mM' value='0.266'/>
<parameter id='KPGIf6ppginh' metaid='_515437' units='mM' value='0.2'/>
<parameter id='KPGIg6ppginh' metaid='_515449' units='mM' value='0.2'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPGM' metaid='_704983' name='Phosphoglucomutase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_704983'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_605'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00959'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/5.4.2.2'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_515461' species='cg6p'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_515473' species='cg1p'/>
</listOfProducts>
<kineticLaw metaid='_515485'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxPGM </ci>
<apply>
<minus/>
<ci> cg6p </ci>
<apply>
<divide/>
<ci> cg1p </ci>
<ci> KPGMeq </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> KPGMg6p </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cg1p </ci>
<ci> KPGMg1p </ci>
</apply>
</apply>
</apply>
<ci> cg6p </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxPGM' metaid='_515497' units='mM_per_second' value='0.8398242773'/>
<parameter id='KPGMeq' metaid='_515509' units='dimensionless' value='0.196'/>
<parameter id='KPGMg6p' metaid='_515521' units='mM' value='1.038'/>
<parameter id='KPGMg1p' metaid='_515533' units='mM' value='0.0136'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vG6PDH' metaid='_705003' name='Glucose-6-phosphate dehydrogenase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705003'>
<bqbiol:hasPart>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00835'/>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R02035'/>
</rdf:Bag>
</bqbiol:hasPart>
<bqbiol:hasPart>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/1.1.1.49'/>
<rdf:li rdf:resource='http://identifiers.org/ec-code/3.1.1.31'/>
</rdf:Bag>
</bqbiol:hasPart>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_515545' species='cg6p'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_515557' species='cpg'/>
</listOfProducts>
<kineticLaw metaid='_515569'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxG6PDH </ci>
<ci> cg6p </ci>
<ci> cnadp </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> cg6p </ci>
<ci> KG6PDHg6p </ci>
</apply>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cnadph </ci>
<ci> KG6PDHnadphg6pinh </ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> KG6PDHnadp </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cnadph </ci>
<ci> KG6PDHnadphnadpinh </ci>
</apply>
</apply>
</apply>
<ci> cnadp </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxG6PDH' metaid='_515581' units='mM_per_second' value='1.380196955'/>
<parameter id='KG6PDHg6p' metaid='_515593' units='mM' value='14.4'/>
<parameter id='KG6PDHnadphg6pinh' metaid='_515605' units='mM' value='6.43'/>
<parameter id='KG6PDHnadp' metaid='_515617' units='mM' value='0.0246'/>
<parameter id='KG6PDHnadphnadpinh' metaid='_515629' units='mM' value='0.01'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPFK' metaid='_705023' name='Phosphofructokinase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705023'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_736'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00756'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/2.7.1.11'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_515641' species='cf6p'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_515653' species='cfdp'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid='_515665' species='cpep'/>
</listOfModifiers>
<kineticLaw metaid='_515677'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxPFK </ci>
<ci> catp </ci>
<ci> cf6p </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> catp </ci>
<apply>
<times/>
<ci> KPFKatps </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cadp </ci>
<ci> KPFKadpc </ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> cf6p </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> KPFKf6ps </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cpep </ci>
<ci> KPFKpep </ci>
</apply>
<apply>
<divide/>
<ci> cadp </ci>
<ci> KPFKadpb </ci>
</apply>
<apply>
<divide/>
<ci> camp </ci>
<ci> KPFKampb </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cadp </ci>
<ci> KPFKadpa </ci>
</apply>
<apply>
<divide/>
<ci> camp </ci>
<ci> KPFKampa </ci>
</apply>
</apply>
</apply>
</apply>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> LPFK </ci>
<apply>
<power/>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<apply>
<times/>
<ci> cf6p </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cadp </ci>
<ci> KPFKadpa </ci>
</apply>
<apply>
<divide/>
<ci> camp </ci>
<ci> KPFKampa </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<ci> KPFKf6ps </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cpep </ci>
<ci> KPFKpep </ci>
</apply>
<apply>
<divide/>
<ci> cadp </ci>
<ci> KPFKadpb </ci>
</apply>
<apply>
<divide/>
<ci> camp </ci>
<ci> KPFKampb </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
<ci> nPFK </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxPFK' metaid='_515689' units='mM_per_second' value='1840.584747'/>
<parameter id='KPFKatps' metaid='_515701' units='mM' value='0.123'/>
<parameter id='KPFKadpc' metaid='_515713' units='mM' value='4.14'/>
<parameter id='KPFKf6ps' metaid='_515726' units='mM' value='0.325'/>
<parameter id='KPFKpep' metaid='_515738' units='mM' value='3.26'/>
<parameter id='KPFKadpb' metaid='_515750' units='mM' value='3.89'/>
<parameter id='KPFKampb' metaid='_515762' units='mM' value='3.2'/>
<parameter id='KPFKadpa' metaid='_515774' units='mM' value='128'/>
<parameter id='KPFKampa' metaid='_515786' units='mM' value='19.1'/>
<parameter id='LPFK' metaid='_515798' units='dimensionless' value='5629067'/>
<parameter id='nPFK' metaid='_515810' units='dimensionless' value='11.1'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vTA' metaid='_705043' name='Transaldolase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705043'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_1272'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01827'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/2.2.1.2'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_515822' species='cgap'/>
<speciesReference metaid='_515834' species='csed7p'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_515846' species='cf6p'/>
<speciesReference metaid='_515858' species='ce4p'/>
</listOfProducts>
<kineticLaw metaid='_515870'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxTA </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> cgap </ci>
<ci> csed7p </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> ce4p </ci>
<ci> cf6p </ci>
</apply>
<ci> KTAeq </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxTA' metaid='_515882' units='per_mM_per_second' value='10.87164108'/>
<parameter id='KTAeq' metaid='_515894' units='dimensionless' value='1.05'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vTKA' metaid='_705063' name='Transketolase a'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705063'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_162'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01641'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/2.2.1.1'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_515906' species='crib5p'/>
<speciesReference metaid='_515918' species='cxyl5p'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_515930' species='cgap'/>
<speciesReference metaid='_515942' species='csed7p'/>
</listOfProducts>
<kineticLaw metaid='_515954'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxTKa </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> crib5p </ci>
<ci> cxyl5p </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> csed7p </ci>
<ci> cgap </ci>
</apply>
<ci> KTKaeq </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxTKa' metaid='_515966' units='per_mM_per_second' value='9.473384783'/>
<parameter id='KTKaeq' metaid='_515979' units='dimensionless' value='1.2'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vTKB' metaid='_705083' name='Transketolase b'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705083'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_1811'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01067'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/2.2.1.1'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_515991' species='ce4p'/>
<speciesReference metaid='_516003' species='cxyl5p'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_516015' species='cgap'/>
<speciesReference metaid='_516027' species='cf6p'/>
</listOfProducts>
<kineticLaw metaid='_516039'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxTKb </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> cxyl5p </ci>
<ci> ce4p </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> cf6p </ci>
<ci> cgap </ci>
</apply>
<ci> KTKbeq </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxTKb' metaid='_516051' units='per_mM_per_second' value='86.55855855'/>
<parameter id='KTKbeq' metaid='_516063' units='dimensionless' value='10'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vMURSyNTH' metaid='_705103' name='Mureine synthesis'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705103'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0006002'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516075' species='cf6p' stoichiometry='2'/>
</listOfReactants>
<kineticLaw metaid='_516087'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxMurSynth </ci>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxMurSynth' metaid='_516099' units='mM_per_second' value='0.00043711'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vALDO' metaid='_705123' name='Aldolase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705123'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_1602'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01070'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/4.1.2.13'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516111' species='cfdp'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_516123' species='cdhap'/>
<speciesReference metaid='_516135' species='cgap'/>
</listOfProducts>
<kineticLaw metaid='_516147'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxALDO </ci>
<apply>
<minus/>
<ci> cfdp </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> cgap </ci>
<ci> cdhap </ci>
</apply>
<ci> kALDOeq </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> kALDOfdp </ci>
<ci> cfdp </ci>
<apply>
<divide/>
<apply>
<times/>
<ci> kALDOgap </ci>
<ci> cdhap </ci>
</apply>
<apply>
<times/>
<ci> kALDOeq </ci>
<ci> VALDOblf </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> kALDOdhap </ci>
<ci> cgap </ci>
</apply>
<apply>
<times/>
<ci> kALDOeq </ci>
<ci> VALDOblf </ci>
</apply>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> cfdp </ci>
<ci> cgap </ci>
</apply>
<ci> kALDOgapinh </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> cgap </ci>
<ci> cdhap </ci>
</apply>
<apply>
<times/>
<ci> VALDOblf </ci>
<ci> kALDOeq </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxALDO' metaid='_516159' units='mM_per_second' value='17.41464425'/>
<parameter id='kALDOeq' metaid='_516171' units='mM' value='0.144'/>
<parameter id='kALDOfdp' metaid='_516183' units='mM' value='1.75'/>
<parameter id='kALDOgap' metaid='_516195' units='mM' value='0.088'/>
<parameter id='VALDOblf' metaid='_516207' units='dimensionless' value='2'/>
<parameter id='kALDOdhap' metaid='_516219' units='mM' value='0.088'/>
<parameter id='kALDOgapinh' metaid='_516231' units='mM' value='0.6'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vGAPDH' metaid='_705143' name='Glyceraldehyde-3-phosphate dehydrogenase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705143'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_1847'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01061'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/1.2.1.12'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516243' species='cgap'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_516255' species='cpgp'/>
</listOfProducts>
<kineticLaw metaid='_516267'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxGAPDH </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> cgap </ci>
<ci> cnad </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> cpgp </ci>
<ci> cnadh </ci>
</apply>
<ci> KGAPDHeq </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<times/>
<ci> KGAPDHgap </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cpgp </ci>
<ci> KGAPDHpgp </ci>
</apply>
</apply>
</apply>
<ci> cgap </ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> KGAPDHnad </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cnadh </ci>
<ci> KGAPDHnadh </ci>
</apply>
</apply>
</apply>
<ci> cnad </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxGAPDH' metaid='_516279' units='mM_per_second' value='921.5942861'/>
<parameter id='KGAPDHeq' metaid='_516291' units='dimensionless' value='0.63'/>
<parameter id='KGAPDHgap' metaid='_516303' units='mM' value='0.683'/>
<parameter id='KGAPDHpgp' metaid='_516315' units='mM' value='1.04E-5'/>
<parameter id='KGAPDHnad' metaid='_516327' units='mM' value='0.252'/>
<parameter id='KGAPDHnadh' metaid='_516339' units='mM' value='1.09'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vTIS' metaid='_705163' name='Triosephosphate isomerase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705163'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_469'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01015'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/5.3.1.1'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516351' species='cdhap'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_516363' species='cgap'/>
</listOfProducts>
<kineticLaw metaid='_516375'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxTIS </ci>
<apply>
<minus/>
<ci> cdhap </ci>
<apply>
<divide/>
<ci> cgap </ci>
<ci> kTISeq </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> kTISdhap </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cgap </ci>
<ci> kTISgap </ci>
</apply>
</apply>
</apply>
<ci> cdhap </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxTIS' metaid='_516387' units='mM_per_second' value='68.67474392'/>
<parameter id='kTISeq' metaid='_516399' units='dimensionless' value='1.39'/>
<parameter id='kTISdhap' metaid='_516411' units='mM' value='2.8'/>
<parameter id='kTISgap' metaid='_516423' units='mM' value='0.3'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vTRPSYNTH' metaid='_705183' name='Tryptophan synthesis'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705183'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0000162'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfProducts>
<speciesReference metaid='_516435' species='cpyr'/>
<speciesReference metaid='_516447' species='cgap'/>
</listOfProducts>
<kineticLaw metaid='_516459'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxTrpSynth </ci>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxTrpSynth' metaid='_516471' units='mM_per_second' value='0.001037'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vG3PDH' metaid='_705203' name='Glycerol-3-phosphate dehydrogenase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705203'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_16938'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00842'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/1.1.1.8'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516483' species='cdhap'/>
</listOfReactants>
<kineticLaw metaid='_516495'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxG3PDH </ci>
<ci> cdhap </ci>
</apply>
<apply>
<plus/>
<ci> KG3PDHdhap </ci>
<ci> cdhap </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxG3PDH' metaid='_516507' units='mM_per_second' value='0.01162042696'/>
<parameter id='KG3PDHdhap' metaid='_516519' units='mM' value='1'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPGK' metaid='_705223' name='Phosphoglycerate kinase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705223'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_1186'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01512'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/2.7.2.3'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516531' species='cpgp'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_516543' species='cpg3'/>
</listOfProducts>
<kineticLaw metaid='_516555'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxPGK </ci>
<apply>
<minus/>
<apply>
<times/>
<ci> cadp </ci>
<ci> cpgp </ci>
</apply>
<apply>
<divide/>
<apply>
<times/>
<ci> catp </ci>
<ci> cpg3 </ci>
</apply>
<ci> KPGKeq </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<apply>
<times/>
<ci> KPGKadp </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> catp </ci>
<ci> KPGKatp </ci>
</apply>
</apply>
</apply>
<ci> cadp </ci>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> KPGKpgp </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cpg3 </ci>
<ci> KPGKpg3 </ci>
</apply>
</apply>
</apply>
<ci> cpgp </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxPGK' metaid='_516567' units='mM_per_second' value='3021.773771'/>
<parameter id='KPGKeq' metaid='_516580' units='dimensionless' value='1934.4'/>
<parameter id='KPGKadp' metaid='_516592' units='mM' value='0.185'/>
<parameter id='KPGKatp' metaid='_516604' units='mM' value='0.653'/>
<parameter id='KPGKpgp' metaid='_516616' units='mM' value='0.0468'/>
<parameter id='KPGKpg3' metaid='_516628' units='mM' value='0.473'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vsersynth' metaid='_705243' name='Serine synthesis'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705243'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0009070'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516640' species='cpg3'/>
</listOfReactants>
<kineticLaw metaid='_516652'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxSerSynth </ci>
<ci> cpg3 </ci>
</apply>
<apply>
<plus/>
<ci> KSerSynthpg3 </ci>
<ci> cpg3 </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxSerSynth' metaid='_516664' units='mM_per_second' value='0.025712107'/>
<parameter id='KSerSynthpg3' metaid='_516676' units='mM' value='1'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vrpGluMu' metaid='_705263' name='Phosphoglycerate mutase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705263'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_576'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01518'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/5.4.2.1'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516688' species='cpg3'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_516700' species='cpg2'/>
</listOfProducts>
<kineticLaw metaid='_516712'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxPGluMu </ci>
<apply>
<minus/>
<ci> cpg3 </ci>
<apply>
<divide/>
<ci> cpg2 </ci>
<ci> KPGluMueq </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> KPGluMupg3 </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cpg2 </ci>
<ci> KPGluMupg2 </ci>
</apply>
</apply>
</apply>
<ci> cpg3 </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxPGluMu' metaid='_516724' units='mM_per_second' value='89.04965407'/>
<parameter id='KPGluMueq' metaid='_516736' units='dimensionless' value='0.188'/>
<parameter id='KPGluMupg3' metaid='_516748' units='mM' value='0.2'/>
<parameter id='KPGluMupg2' metaid='_516760' units='mM' value='0.369'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vENO' metaid='_705283' name='Enolase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705283'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_1400'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00658'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/4.2.1.11'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516772' species='cpg2'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_516784' species='cpep'/>
</listOfProducts>
<kineticLaw metaid='_516796'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxENO </ci>
<apply>
<minus/>
<ci> cpg2 </ci>
<apply>
<divide/>
<ci> cpep </ci>
<ci> KENOeq </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<apply>
<times/>
<ci> KENOpg2 </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cpep </ci>
<ci> KENOpep </ci>
</apply>
</apply>
</apply>
<ci> cpg2 </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxENO' metaid='_516808' units='mM_per_second' value='330.4476151'/>
<parameter id='KENOeq' metaid='_516820' units='mM' value='6.73'/>
<parameter id='KENOpg2' metaid='_516832' units='mM' value='0.1'/>
<parameter id='KENOpep' metaid='_516844' units='mM' value='0.135'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPK' metaid='_705303' name='Pyruvate kinase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705303'>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_1524'/>
</rdf:Bag>
</bqbiol:isHomologTo>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00200'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/2.7.1.40'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_516856' species='cpep'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_516868' species='cpyr'/>
</listOfProducts>
<listOfModifiers>
<modifierSpeciesReference metaid='_516880' species='cfdp'/>
</listOfModifiers>
<kineticLaw metaid='_516892'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxPK </ci>
<ci> cpep </ci>
<apply>
<power/>
<apply>
<plus/>
<apply>
<divide/>
<ci> cpep </ci>
<ci> KPKpep </ci>
</apply>
<cn type='integer'> 1 </cn>
</apply>
<apply>
<minus/>
<ci> nPK </ci>
<cn type='integer'> 1 </cn>
</apply>
</apply>
<ci> cadp </ci>
</apply>
<apply>
<times/>
<ci> KPKpep </ci>
<apply>
<plus/>
<apply>
<times/>
<ci> LPK </ci>
<apply>
<power/>
<apply>
<divide/>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> catp </ci>
<ci> KPKatp </ci>
</apply>
</apply>
<apply>
<plus/>
<apply>
<divide/>
<ci> cfdp </ci>
<ci> KPKfdp </ci>
</apply>
<apply>
<divide/>
<ci> camp </ci>
<ci> KPKamp </ci>
</apply>
<cn type='integer'> 1 </cn>
</apply>
</apply>
<ci> nPK </ci>
</apply>
</apply>
<apply>
<power/>
<apply>
<plus/>
<apply>
<divide/>
<ci> cpep </ci>
<ci> KPKpep </ci>
</apply>
<cn type='integer'> 1 </cn>
</apply>
<ci> nPK </ci>
</apply>
</apply>
<apply>
<plus/>
<ci> cadp </ci>
<ci> KPKadp </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxPK' metaid='_516904' units='mM_per_second' value='0.06113150238'/>
<parameter id='KPKpep' metaid='_516916' units='mM' value='0.31'/>
<parameter id='nPK' metaid='_516928' units='dimensionless' value='4'/>
<parameter id='LPK' metaid='_516940' units='dimensionless' value='1000'/>
<parameter id='KPKatp' metaid='_516952' units='mM' value='22.5'/>
<parameter id='KPKfdp' metaid='_516964' units='mM' value='0.19'/>
<parameter id='KPKamp' metaid='_516976' units='mM' value='0.2'/>
<parameter id='KPKadp' metaid='_516988' units='mM' value='0.26'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vpepCxylase' metaid='_705323' name='PEP carboxylase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705323'>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00345'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/4.1.1.31'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517000' species='cpep'/>
</listOfReactants>
<listOfModifiers>
<modifierSpeciesReference metaid='_517012' species='cfdp'/>
</listOfModifiers>
<kineticLaw metaid='_517024'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxpepCxylase </ci>
<ci> cpep </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<power/>
<apply>
<divide/>
<ci> cfdp </ci>
<ci> KpepCxylasefdp </ci>
</apply>
<ci> npepCxylasefdp </ci>
</apply>
</apply>
</apply>
<apply>
<plus/>
<ci> KpepCxylasepep </ci>
<ci> cpep </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxpepCxylase' metaid='_517036' units='mM_per_second' value='0.1070205858'/>
<parameter id='KpepCxylasefdp' metaid='_517048' units='mM' value='0.7'/>
<parameter id='npepCxylasefdp' metaid='_517060' units='dimensionless' value='4.21'/>
<parameter id='KpepCxylasepep' metaid='_517073' units='mM' value='4.07'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vSynth1' metaid='_705343' name='Synthesis 1'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705343'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0009423'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517085' species='cpep'/>
</listOfReactants>
<kineticLaw metaid='_517097'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxSynth1 </ci>
<ci> cpep </ci>
</apply>
<apply>
<plus/>
<ci> KSynth1pep </ci>
<ci> cpep </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxSynth1' metaid='_517109' units='mM_per_second' value='0.01953897003'/>
<parameter id='KSynth1pep' metaid='_517121' units='mM' value='1'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vSynth2' metaid='_705363' name='Synthesis 2'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705363'>
<bqbiol:hasPart>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0006523'/>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0009097'/>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0019877'/>
</rdf:Bag>
</bqbiol:hasPart>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517133' species='cpyr'/>
</listOfReactants>
<kineticLaw metaid='_517145'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxSynth2 </ci>
<ci> cpyr </ci>
</apply>
<apply>
<plus/>
<ci> KSynth2pyr </ci>
<ci> cpyr </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxSynth2' metaid='_517157' units='mM_per_second' value='0.07361855055'/>
<parameter id='KSynth2pyr' metaid='_517169' units='mM' value='1'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vDAHPS' metaid='_705383' name='DAHP synthesis'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705383'>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01826'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/2.5.1.54'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517182' species='ce4p'/>
<speciesReference metaid='_517194' species='cpep'/>
</listOfReactants>
<kineticLaw metaid='_517207'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxDAHPS </ci>
<apply>
<power/>
<ci> ce4p </ci>
<ci> nDAHPSe4p </ci>
</apply>
<apply>
<power/>
<ci> cpep </ci>
<ci> nDAHPSpep </ci>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> KDAHPSe4p </ci>
<apply>
<power/>
<ci> ce4p </ci>
<ci> nDAHPSe4p </ci>
</apply>
</apply>
<apply>
<plus/>
<ci> KDAHPSpep </ci>
<apply>
<power/>
<ci> cpep </ci>
<ci> nDAHPSpep </ci>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxDAHPS' metaid='_517219' units='mM_per_second' value='0.1079531227'/>
<parameter id='nDAHPSe4p' metaid='_517231' units='dimensionless' value='2.6'/>
<parameter id='nDAHPSpep' metaid='_517243' units='dimensionless' value='2.2'/>
<parameter id='KDAHPSe4p' metaid='_517256' units='mM' value='0.035'/>
<parameter id='KDAHPSpep' metaid='_517268' units='mM' value='0.0053'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPDH' metaid='_705403' name='Pyruvate dehydrogenase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705403'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/1.2.1.51'/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00209'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isPartOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.pathway/rn00620'/>
</rdf:Bag>
</bqbiol:isPartOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517280' species='cpyr'/>
</listOfReactants>
<kineticLaw metaid='_517295'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxPDH </ci>
<apply>
<power/>
<ci> cpyr </ci>
<ci> nPDH </ci>
</apply>
</apply>
<apply>
<plus/>
<ci> KPDHpyr </ci>
<apply>
<power/>
<ci> cpyr </ci>
<ci> nPDH </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxPDH' metaid='_517307' units='mM_per_second' value='6.059531017'/>
<parameter id='nPDH' metaid='_517319' units='dimensionless' value='3.68'/>
<parameter id='KPDHpyr' metaid='_517331' units='mM' value='1159'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vMethSynth' metaid='_705423' name='Methionine synthesis'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705423'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0042866'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfProducts>
<speciesReference metaid='_517343' species='cpyr'/>
</listOfProducts>
<kineticLaw metaid='_517355'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxMetSynth </ci>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxMetSynth' metaid='_517367' units='mM_per_second' value='0.0022627'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPGDH' metaid='_705443' name='6-Phosphogluconate dehydrogenase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705443'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/1.1.1.44'/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01528'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_611'/>
</rdf:Bag>
</bqbiol:isHomologTo>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517379' species='cpg'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_517391' species='cribu5p'/>
</listOfProducts>
<kineticLaw metaid='_517403'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxPGDH </ci>
<ci> cpg </ci>
<ci> cnadp </ci>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> cpg </ci>
<ci> KPGDHpg </ci>
</apply>
<apply>
<plus/>
<ci> cnadp </ci>
<apply>
<times/>
<ci> KPGDHnadp </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> cnadph </ci>
<ci> KPGDHnadphinh </ci>
</apply>
</apply>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<divide/>
<ci> catp </ci>
<ci> KPGDHatpinh </ci>
</apply>
</apply>
</apply>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxPGDH' metaid='_517415' units='mM_per_second' value='16.23235977'/>
<parameter id='KPGDHpg' metaid='_517427' units='mM' value='37.5'/>
<parameter id='KPGDHnadp' metaid='_517439' units='mM' value='0.0506'/>
<parameter id='KPGDHnadphinh' metaid='_517451' units='mM' value='0.0138'/>
<parameter id='KPGDHatpinh' metaid='_517464' units='mM' value='208'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vR5PI' metaid='_705463' name='Ribose-phosphate isomerase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705463'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/5.3.1.6'/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01056'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_6907'/>
</rdf:Bag>
</bqbiol:isHomologTo>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517476' species='cribu5p'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_517488' species='crib5p'/>
</listOfProducts>
<kineticLaw metaid='_517500'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxR5PI </ci>
<apply>
<minus/>
<ci> cribu5p </ci>
<apply>
<divide/>
<ci> crib5p </ci>
<ci> KR5PIeq </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxR5PI' metaid='_517512' units='second_inverse' value='4.83841193'/>
<parameter id='KR5PIeq' metaid='_517524' units='dimensionless' value='4'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vRu5P' metaid='_705483' name='Ribulose-phosphate epimerase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705483'>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01529'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/5.1.3.1'/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_1522'/>
</rdf:Bag>
</bqbiol:isHomologTo>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517537' species='cribu5p'/>
</listOfReactants>
<listOfProducts>
<speciesReference metaid='_517549' species='cxyl5p'/>
</listOfProducts>
<kineticLaw metaid='_517561'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxRu5P </ci>
<apply>
<minus/>
<ci> cribu5p </ci>
<apply>
<divide/>
<ci> cxyl5p </ci>
<ci> KRu5Peq </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxRu5P' metaid='_517573' units='second_inverse' value='6.739029475'/>
<parameter id='KRu5Peq' metaid='_517585' units='dimensionless' value='1.4'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPPK' metaid='_705503' name='Ribose phosphate pyrophosphokinase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705503'>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R01049'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/2.7.6.1'/>
</rdf:Bag>
</bqbiol:isVersionOf>
<bqbiol:isHomologTo>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/reactome/REACT_2023'/>
</rdf:Bag>
</bqbiol:isHomologTo>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517598' species='crib5p'/>
</listOfReactants>
<kineticLaw metaid='_517611'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxRPPK </ci>
<ci> crib5p </ci>
</apply>
<apply>
<plus/>
<ci> KRPPKrib5p </ci>
<ci> crib5p </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxRPPK' metaid='_517623' units='mM_per_second' value='0.01290045226'/>
<parameter id='KRPPKrib5p' metaid='_517635' units='mM' value='0.1'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vG1PAT' metaid='_705504' name='Glucose-1-phosphate adenyltransferase'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705504'>
<bqbiol:is>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/kegg.reaction/R00948'/>
</rdf:Bag>
</bqbiol:is>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/ec-code/2.7.7.27'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517647' species='cg1p'/>
</listOfReactants>
<listOfModifiers>
<modifierSpeciesReference metaid='_517659' species='cfdp'/>
</listOfModifiers>
<kineticLaw metaid='_517671'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<divide/>
<apply>
<times/>
<ci> cytosol </ci>
<ci> rmaxG1PAT </ci>
<ci> cg1p </ci>
<ci> catp </ci>
<apply>
<plus/>
<cn type='integer'> 1 </cn>
<apply>
<power/>
<apply>
<divide/>
<ci> cfdp </ci>
<ci> KG1PATfdp </ci>
</apply>
<ci> nG1PATfdp </ci>
</apply>
</apply>
</apply>
<apply>
<times/>
<apply>
<plus/>
<ci> KG1PATatp </ci>
<ci> catp </ci>
</apply>
<apply>
<plus/>
<ci> KG1PATg1p </ci>
<ci> cg1p </ci>
</apply>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='rmaxG1PAT' metaid='_517683' units='mM_per_second' value='0.007525458026'/>
<parameter id='KG1PATfdp' metaid='_517695' units='mM' value='0.119'/>
<parameter id='nG1PATfdp' metaid='_517707' units='mM' value='1.2'/>
<parameter id='KG1PATatp' metaid='_517719' units='mM' value='4.42'/>
<parameter id='KG1PATg1p' metaid='_517731' units='mM' value='3.2'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vG6P' metaid='_705523' name='G6P degradation'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705523'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0044275'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517743' species='cg6p'/>
</listOfReactants>
<kineticLaw metaid='_517755'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cg6p </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_517767' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vf6P' metaid='_705543' name='F6P degradation'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705543'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0044275'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517779' species='cf6p'/>
</listOfReactants>
<kineticLaw metaid='_517791'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cf6p </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_517803' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vfdP' metaid='_705563' name='FDP degradation'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705563'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0044275'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517815' species='cfdp'/>
</listOfReactants>
<kineticLaw metaid='_517827'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cfdp </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_517839' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vGAP' metaid='_705583' name='GAP degradation'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705583'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0019683'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517851' species='cgap'/>
</listOfReactants>
<kineticLaw metaid='_517863'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cgap </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_517876' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vDHAP' metaid='_705603' name='DHAP degradation'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705603'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0044275'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517888' species='cdhap'/>
</listOfReactants>
<kineticLaw metaid='_517901'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cdhap </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_517913' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPGP' metaid='_705623' name='PGP degradation'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705623'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0044275'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517925' species='cpgp'/>
</listOfReactants>
<kineticLaw metaid='_517937'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cpgp </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_517949' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPG3' metaid='_705643' name='PG3 degradation'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705643'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0044275'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517961' species='cpg3'/>
</listOfReactants>
<kineticLaw metaid='_517973'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cpg3 </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_517985' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vpg2' metaid='_705645' name='PG2 degradation'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705645'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0044275'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_517997' species='cpg2'/>
</listOfReactants>
<kineticLaw metaid='_518009'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cpg2 </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518021' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPEP' metaid='_705663' name='PEP degradation'>
<annotation>
<rdf:RDF xmlns:bqbiol='http://biomodels.net/biology-qualifiers/' xmlns:bqmodel='http://biomodels.net/model-qualifiers/' xmlns:rdf='http://www.w3.org/1999/02/22-rdf-syntax-ns#'>
<rdf:Description rdf:about='#_705663'>
<bqbiol:isVersionOf>
<rdf:Bag>
<rdf:li rdf:resource='http://identifiers.org/obo.go/GO:0046395'/>
</rdf:Bag>
</bqbiol:isVersionOf>
</rdf:Description>
</rdf:RDF>
</annotation>
<listOfReactants>
<speciesReference metaid='_518033' species='cpep'/>
</listOfReactants>
<kineticLaw metaid='_518045'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cpep </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518057' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vRibu5p' metaid='_705683' name='Ribu5P dilution'>
<listOfReactants>
<speciesReference metaid='_518069' species='cribu5p'/>
</listOfReactants>
<kineticLaw metaid='_518081'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cribu5p </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518093' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vRIB5P' metaid='_705684' name='Rib5P dilution'>
<listOfReactants>
<speciesReference metaid='_518105' species='crib5p'/>
</listOfReactants>
<kineticLaw metaid='_518117'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> crib5p </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518129' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vXYL5P' metaid='_705703' name='XYL5P dilution'>
<listOfReactants>
<speciesReference metaid='_518141' species='cxyl5p'/>
</listOfReactants>
<kineticLaw metaid='_518153'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cxyl5p </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518165' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vSED7P' metaid='_705723' name='SED7P dilution'>
<listOfReactants>
<speciesReference metaid='_518178' species='csed7p'/>
</listOfReactants>
<kineticLaw metaid='_518190'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> csed7p </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518203' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vpyr' metaid='_705743' name='Pyruvate dilution'>
<listOfReactants>
<speciesReference metaid='_518216' species='cpyr'/>
</listOfReactants>
<kineticLaw metaid='_518229'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cpyr </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518242' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vPG' metaid='_705763' name='PG dilution'>
<listOfReactants>
<speciesReference metaid='_518255' species='cpg'/>
</listOfReactants>
<kineticLaw metaid='_518267'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cpg </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518279' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vE4P' metaid='_705783' name='E4P dilution'>
<listOfReactants>
<speciesReference metaid='_518291' species='ce4p'/>
</listOfReactants>
<kineticLaw metaid='_518304'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> ce4p </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518317' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vGLP' metaid='_705803' name='GLP dilution'>
<listOfReactants>
<speciesReference metaid='_518330' species='cg1p'/>
</listOfReactants>
<kineticLaw metaid='_518343'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> cytosol </ci>
<ci> mu </ci>
<ci> cg1p </ci>
</apply>
</math>
<listOfParameters>
<parameter id='mu' metaid='_518356' units='second_inverse' value='2.78E-5'/>
</listOfParameters>
</kineticLaw>
</reaction>
<reaction id='vEXTER' metaid='_705823' name='Extracellular glucose kinetics'>
<listOfProducts>
<speciesReference metaid='_518369' species='cglcex'/>
</listOfProducts>
<kineticLaw metaid='_518382'>
<math xmlns='http://www.w3.org/1998/Math/MathML'>
<apply>
<times/>
<ci> extracellular </ci>
<ci> Dil </ci>
<apply>
<minus/>
<ci> cfeed </ci>
<ci> cglcex </ci>
</apply>
</apply>
</math>
<listOfParameters>
<parameter id='Dil' metaid='_518395' units='second_inverse' value='2.78E-5'/>
<parameter id='cfeed' metaid='_518408' units='mM' value='110.96'/>
</listOfParameters>
</kineticLaw>
</reaction>
</listOfReactions>
</model>
</sbml>
Simulation of BIOMD0000000051.xml |
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| Notes |
Original model source: in BioModels database.
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| Software | not specified | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| BioModels or JWS Online ID | BIOMD0000000051 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Export metadata |
RDF:
metadataModelEntryID13.rdf
XML: metadataModelEntryID13.xml Plain text: metadataModelEntryID13.txt |
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cg6p + cpyr
Share
|
Cite Model EntryID 13
Cite Model EntryID 13
| APA |
KiMoSys (https://kimosys.org). (2014, April 25). Model EntryID 13 (Escherichia coli). https://kimosys.org/repository/30/associated_models/13
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| MLA |
KiMoSys (https://kimosys.org). "Model EntryID 13 (Escherichia coli)." 2024, kimosys.org/repository/30/associated_models/13.
|
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| ISO-690 |
KiMoSys (https://kimosys.org). Model EntryID 13 (Escherichia coli). [online], [Accessed 25 April 2024]. Available from: https://kimosys.org/repository/30/associated_models/13
|
|
| BibTeX |
@misc{ KiMoSysModelEntryID13,
author = "{KiMoSys (https://kimosys.org)}",
title = "Model EntryID 13 (Escherichia coli)",
url = "https://kimosys.org/repository/30/associated_models/13",
note = "[Online; accessed 25-April-2024]"
}
|
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Related Model(s): AccessID 16 | AccessID 25 | AccessID 36 | AccessID 38 | AccessID 40 | AccessID 42 | AccessID 43 | AccessID 44 | AccessID 45
Submission and curation
Entered by:
Administrator KiMoSysFirst name: Administrator
Affiliation: INESC-ID/IST
Homepage: http://kdbio.inesc-id.pt/kimosys
Interests: mathematical modeling, accessible data, use of data
Created: 2013-03-06 19:18:54 UTC
Updated: 2014-06-30 17:38:01 UTC
Version: 0
Status: (reviewed) 2013-12-06 18:05:50 UTC
Views: 277
Downloads: 91